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Year Number of Results
2010 1
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2015 2
2016 1
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12 results

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Page 1
The NOX toolbox: validating the role of NADPH oxidases in physiology and disease.
Altenhöfer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ, Schiffers P, Ho H, Wingler K, Schmidt HH. Altenhöfer S, et al. Among authors: kleikers pw. Cell Mol Life Sci. 2012 Jul;69(14):2327-43. doi: 10.1007/s00018-012-1010-9. Epub 2012 May 31. Cell Mol Life Sci. 2012. PMID: 22648375 Free PMC article. Review.
From single drug targets to synergistic network pharmacology in ischemic stroke.
Casas AI, Hassan AA, Larsen SJ, Gomez-Rangel V, Elbatreek M, Kleikers PWM, Guney E, Egea J, López MG, Baumbach J, Schmidt HHHW. Casas AI, et al. Among authors: kleikers pwm. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7129-7136. doi: 10.1073/pnas.1820799116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894481 Free PMC article.
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Elbatreek MH, Sadegh S, Anastasi E, Guney E, Nogales C, Kacprowski T, Hassan AA, Teubner A, Huang PH, Hsu CY, Schiffers PMH, Janssen GM, Kleikers PWM, Wipat A, Baumbach J, De Mey JGR, Schmidt HHHW. Elbatreek MH, et al. Among authors: kleikers pwm. PLoS Biol. 2020 Nov 10;18(11):e3000885. doi: 10.1371/journal.pbio.3000885. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33170835 Free PMC article.
VAS2870 is a pan-NADPH oxidase inhibitor.
Wingler K, Altenhoefer SA, Kleikers PW, Radermacher KA, Kleinschnitz C, Schmidt HH. Wingler K, et al. Among authors: kleikers pw. Cell Mol Life Sci. 2012 Sep;69(18):3159-60. doi: 10.1007/s00018-012-1107-1. Epub 2012 Aug 9. Cell Mol Life Sci. 2012. PMID: 22875281 No abstract available.
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW. Casas AI, et al. Among authors: kleikers pwm. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12315-12320. doi: 10.1073/pnas.1705034114. Epub 2017 Oct 31. Proc Natl Acad Sci U S A. 2017. PMID: 29087944 Free PMC article.
A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.
Langhauser F, Casas AI, Dao VT, Guney E, Menche J, Geuss E, Kleikers PWM, López MG, Barabási AL, Kleinschnitz C, Schmidt HHHW. Langhauser F, et al. Among authors: kleikers pwm. NPJ Syst Biol Appl. 2018 Feb 5;4:8. doi: 10.1038/s41540-017-0039-7. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29423274 Free PMC article.
12 results